The relationship between reduced glutathione level and glutathione S-transferase activity in sheep erythrocytes.

CHANGES IN GLUTATHIONE S-TRANSFERASE ACTIVITY AND ZEARALENONE CONTENT IN SUSCEPTIBLE AND TOLERANT WHEAT HEADS INOCULATED WITH FUSARIUM GRAMINEARUM, THE CAUSAL AGENT OF FUSARIUM HEAD SCAB

Glutathione S-transferase (GST) activity pattern was determined in tolerant (cv. Sumai#3) and susceptible (cv. Falat) wheat heads inoculated with Fusarium graminearum, the causal agent of head scab disease (FHB), during various developmental stages. GST specific activity exhibited a transient pattern in Sumai#3 reaching a maximum level at the milk stage and declining thereafter. GST level in Su...

Antioxidant properties and Glutathione S-transferases inhibitory activity of Alchornea cordifolia leaf extract in Acetaminophen toxicity

Paracetamol (acetaminophen, PCM) is a widely used over-the-counter analgesic and antipyretic drug. Intake of a large dose of PCM may result in severe hepatic necrosis. Oxidative stress is mediated by oxidative capacities of the PCM metabolite (N-acetyl-para-benzo quinoneimine, NAPQI), which covalently binds to proteins and other macromolecules to cause cellular damage. At low doses, NAPQI is ...

Cellular Immune Responses in Sheep against Glutathione S-transferase of Fasciola gigantica

بررسی پلی‌مورفیسم ژنی ایزوآنزیم‌های GSTM1 و GSTP1 و فعالیت آنزیم گلوتاتیون S-ترانسفراز: مردان نابارور ایرانی

Background: Pi-GST and Mu-GST are subclasses of glutathione S-transferase that present on human sperm surface and play an important role against oxidative stress. Therefore, any defects in the enzyme activity may be associated with male infertility.In this study the polymorphisms of GSTM1 and GSTP1 in association with enzyme activity and sperm parameters were studied. Methods: This case-contro...

Expression of cytochrome P450 and glutathione S-transferase in human bone marrow mesenchymal stem cells

Currently several studies are being carried out on various properties of mesenchymal stem cells (MSCs)however there are a few investigations about drug metabolizing properties of these cells. The aim of thisstudy was to measure the key factors involved in drug metabolism in human bone marrow MSCs. For thispurpose, cellular glutathione (GSH), glutathione Stransferase (GSTs) and...